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Kasael
I sometimes use double meditates against 3 mages, that way I am defending when the enemies attack (they have to charge on their first turn, so I don't take damage, but melee enemies will be able to hit me). This build has more Vit than some, but that doesn't mean I want to take more damage than I have to.
As for the groups of 4... The only group I take damage on is the one with the...
Pronghorn Stomper
Infestation Hound
Carrioncorn
Lux Spectre
The rest I can beat without taking damage. This one damages me because it's 3 melee enemies, and their speeds are about the same, so they go on the same turn. I only have time to take out 2 of them (I leave the hound since it deals less damage ;) ).
Because I have a higher speed, I get 2 moves before they go, and 2 moves after they go, so I can kill them in one go.
I will say, I can start on anything that's not a boss. However, due to the nature of the build, I do need to refresh if I miss my eliminate in the first battle or two.
I tend to like starting on and fighting against groups of 4 because of the additional EXP for it only take one extra turn.
Let me know if you'd like a tincture to try out the build, I can send you one for a discount.